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Episodes
| # | Title | Watch |
|---|---|---|
| 1 | Danica Patrick, Diane Lane, Outkast | Play |
| 2 | Adrien Brody, Joely Fisher | Play |
| 3 | Maggie Gyllenhaal, Abigail Breslin | Play |
| 4 | Julianne Moore, David Duchovny | Play |
| 5 | Beyonce | Play |
| 6 | Damon Wayans, Jeff Probst | Play |
| 7 | Dylan McDermott | Play |
| 8 | Hilary Duff, Heidi Klum | Play |
| 9 | Kevin Costner, Ashton Kutcher | Play |
| 10 | Dr. Phil McGraw, Robin McGraw, Lionel Richie | Play |
| 11 | Jaime Pressly, Ty Pennington, Julio Iglesias | Play |
| 12 | Ben Affleck, Fergie, James McGreevey | Play |
| 13 | Usher, Bob Newhart | Play |
| 14 | Jennifer Love Hewitt, Clay Aiken, Jeremy Iversen | Play |
| 15 | Martin Short, Donny Osmond, Arianna Huffington | Play |
| 16 | Ray Liotta, Bridget Moynahan | Play |
| 17 | Victor Garber, Carnie Wilson, Tina Yothers, Natalie Cole | Play |
| 18 | Jamie Lee Curtis, Salma Hayek, America Ferrera, Bob Seger | Play |
| 19 | Patrick Dempsey, Dr. Michelle Bachelet | Play |
| 20 | Cynthia Nixon, Julian McMahon, Dylan Walsh | Play |
| 21 | Dennis Haysbert, Tyler Florence | Play |
| 22 | Morgan Freeman, Scott Wolf | Play |
| 23 | Queen Latifah, Meg Tilly | Play |
| 24 | Whoopi Goldberg, Andy Dick, "Project Runway" finalists | Play |
| 25 | Joan Rivers, Rod Stewart | Play |
| 26 | John Lithgow, Suzanne Somers, Amy Grant | Play |
| 27 | Gloria Estefan, Lynn Sherr | Play |
| 28 | Nick Lachey, Helen Mirren, Arianna Huffington | Play |
| 29 | Alec Baldwin, Indigo Girls | Play |
| 30 | Sigourney Weaver, Dylan Walsh, Julian McMahon, Ruben Studdard | Play |
| 31 | Martha Stewart, Donal Logue | Play |
| 32 | Bill O'Reilly, Kate Walsh, Trinny and Susannah | Play |
| 33 | Tom Bergeron, Elizabeth Edwards, Cheetah Girls | Play |
| 34 | Kirsten Dunst, Jason Schwartzman, Caroline Rhea | Play |
| 35 | Vanessa Williams, Isaac Mizrahi, Sarah Chalke, Geralyn Lucas, guest co-host Judge Glenda Hatchett | Play |
| 36 | Tim Robbins, Elizabeth Perkins, Lonestar | Play |
| 37 | Jane Fonda, Ellen Burstyn | Play |
| 38 | Ricardo Chavira, Phil Rosenthal, John Legend, guest co-host Tara Reid | Play |
| 39 | Nathan Lane, Amy Berg, guest co-host Sade Baderinwa | Play |
| 40 | Hugh Jackman, Kate Winslet, Christine Ebersole | Play |
| 41 | Courtney Love, Penn & Teller, guest co-host Kathie Lee Gifford | Play |
| 42 | Charles Gibson, Joan Collins | Play |
| 43 | Gary Sinise, Kellie Pickler, guest co-host Arthel Neville | Play |
| 44 | Tim Allen, Martin Short, Barry Manilow, guest co-host Arthel Neville | Play |
| 45 | Ed Harris, Skeet Ulrich, Cameron Mathison | Play |
| 46 | Ashley Judd, JoJo | Play |
| 47 | Alec Baldwin, Mario Cantone | Play |
| 48 | Marcia Gay Harden | Play |
| 49 | Kyle MacLachlan; Harry Shearer, Catherine O'Hara, Parker Posey | Play |
| 50 | Guest co-host Jacque Reid, Cindy Crawford, Josh Radnor, Cobie Smulders | Play |
| 51 | Guest co-host Monique Coleman, Anthony Geary, Genie Francis, Chester Gregory II | Play |
| 52 | Gayle King | Play |
| 53 | Jeff Foxworthy, Mike Rowe | Play |
| 54 | Robin Williams | Play |
| 55 | Helen Hunt, Milo Ventimiglia, Masi Oka | Play |
| 56 | Guest co-host Sherri Shepherd, James Spader, Jim Gaffigan | Play |
| 57 | Maura Tierney | Play |
| 58 | Guest co-host Sherri Shepherd, Hugh Jackman, Rachel Weisz, Robert Verdi | Play |
| 59 | Guest Co-Host Amy Holmes, Matthew Broderick, Marlo Thomas, Andrea Bocelli | Play |
| 60 | Guest Co-Host Victoria Rowell | Play |
| 61 | Thomas Gibson, Danny DeVito | Play |
| 62 | Gayle King, Wynonna Judd | Play |
| 63 | Josh Duhamel, Iman, guest co-host Renee Goldsberry | Play |
| 64 | Marla Sokoloff, Kyra Sedgwick, guest co-host Samantha Harris | Play |
| 65 | Jenny McCarthy, Julia Sweeney, the Von Trapps, guest co-host Shaun Robinson | Play |
| 66 | James Brolin, Jeffrey Carlson | Play |
| 67 | Wilmer Valderrama, cast of Broadway's "Mary Poppins" | Play |
| 68 | Dakota Fanning, Mitch Albom, guest co-host Shaun Robinson | Play |
| 69 | Taylor Hicks | Play |
| 70 | Neil Diamond | Play |
| 71 | Bette Midler, Frank Rich | Play |
| 72 | Fantasia, Susan Sarandon, guest co-host Dari Alexander | Play |
| 73 | Gladys Knight, Julianne Moore, guest co-host Dari Alexander | Play |
| 74 | Bryan Fogel, Martha Stewart, Sam Wolfson, guest co-host Sherri Shepherd | Play |
| 75 | Kristin Chenoweth, Judy Gold, Edward Norton, guest co-host Jacque Reid | Play |
| 76 | Sen. Hillary Rodham Clinton, Kaye Ballard, guest co-host Crystal McCrary Anthony | Play |
| 77 | Ewan McGregor, the Children's Christmas Choir | Play |
| 78 | Matthew McConaughey, Matthew Fox, Anthony Mackie, Kate Mara, a performance by the Broadway cast of "Rent" | Play |
| 79 | Cate Blanchett, Carla Gugino, guest co-host Sherri Shepherd | Play |
| 80 | LL Cool J, guest co-host Sherri Shepherd | Play |
| 81 | Erin Gruwell, April L. Hernandez, Donal Logue, Hilary Swank, guest co-host Sherri Shepherd | Play |
| 82 | Lucy Liu, Michael Urie, guest co-host Sherri Shepherd | Play |
| 83 | Nicollette Sheridan, Robert Verdi, guest co-host Sherri Shepherd | Play |
| 84 | Kaley Cuoco, Jennifer Hudson | Play |
| 85 | David Arquette, guest co-host Lola Oguinnaike | Play |
| 86 | Sarah Ferguson, Sam Harris | Play |
| 87 | Cybill Shepherd, guest co-host Kerry Washington | Play |
| 88 | Peter O'Toole | Play |
| 89 | Jo Frost, Patricia Heaton | Play |
| 90 | Mario Cantone, LL Cool J, Nancy Wilson | Play |
| 91 | Rupert Everett, The Wiggles, guest co-host April Lee Hernandez | Play |
| 92 | Juliette Binoche, Raquel Welch, gest co-host Kellie Pickler | Play |
| 93 | Kathy Griffin, Les Stroud, guest co-host Kellie Pickler | Play |
| 94 | Lizzy Caplan, Heather Goldenhersh, Justin Chambers | Play |
| 95 | Tatum O'Neal | Playing |
| 96 | Marc Summers, Forest Whitaker | Play |
| 97 | Tony Danza, Lou Dobbs, guest co-host Tina Fey | Play |
| 98 | Duff Goldman, Jeremy Piven | Play |
| 99 | Guest co-host Toni Braxton | Play |
| 100 | Harry Connick Jr., Kristin Davis, guest co-host Whoopi Goldberg | Play |
| 101 | Mary Hart, guest co-host Jane Krakowski | Play |
| 102 | Sarah Silverman, Marcel Vigneron, Goran Visnjic | Play |
| 103 | Kevin Bacon, Chelsea Handler, Joy Mangano, guest co-host Whoopi Goldberg | Play |
| 104 | Regis Philbin, Sendhil Ramamurthy | Play |
| 105 | Yunjin Kim, Jackie Earle Haley | Play |
| 106 | Miley Cyrus, Emily Deschanel | Play |
| 107 | Hilary Duff, John Tartaglia, guest co-host Kristin Chenoweth | Play |
| 108 | Josh Groban, guest co-host Kristin Chenoweth | Play |
| 109 | Mario Cantone, Eva Longoria | Play |
| 110 | Anita Baker, Dave Koz, John Stamos, guest co-host Jo Frost | Play |
| 111 | Courtney Thorne-Smith | Play |
| 112 | Adrian Pasdar, Eric Mabius | Play |
| 113 | Hugh Grant | Play |
| 114 | Jack Coleman, guest co-host Sherri Shepherd | Play |
| 115 | Richard Lewis, David Tutera, guest co-host Sherri Shepherd | Play |
| 116 | Sienna Miller | Play |
| 117 | Jim Carrey, a performance from the Broadway musical "Spring Awakening" by Remy Zaken | Play |
| 118 | Samuel L. Jackson, Christina Ricci, guest co-host Sherri Shepherd | Play |
| 119 | Tom Bergeron, Angela Lansbury | Play |
| 120 | Cheutine Fong, Jane Seymour, Von Smith, guest co-host Kimberly McCullough | Play |
| 121 | Angela Bassett, Courtney B. Vance | Play |
| 122 | Dennis Miller, Suze Orman | Play |
| 123 | Evangeline Lilly, guest co-host S. Epatha Merkerson | Play |
| 124 | Rachael Ray, Bob and Lee Woodruff | Play |
| 125 | Ken Davitian, Skeet Ulrich, guest co-host Constance Marie | Play |
| 126 | Phyllis Diller, Kelsey Fowler | Play |
| 127 | Queen Latifah, Mark Indelicato, guest co-host Kimberley Locke | Play |
| 128 | Guest co-host Linda Dano | Play |
| 129 | Laura Prepon, Richard Jeni, Minnie Driver, Senator Charles Schumer, guest co-host Jacque Reid | Play |
| 130 | Roseanne, guest co-host Joely Fisher | Play |
| 131 | Delta Burke, guest co-host Susie Essman | Play |
| 132 | Julian McMahon, Rich Little | Play |
| 133 | Chris Rock, Kerry Washington, Cyndi Lauper | Play |
| 134 | Rory Kennedy, Rick Schroder, Nelly Furtado and Timbaland | Play |
| 135 | Bea Arthur, Adrienne Barbeau, guest co-host Audra McDonald | Play |
| 136 | The cast of "A Chorus Line", the cast of "Les Miserables", LaChanze, Elisabeth Withers-Mendes, baker Marjorie Johnson | Play |
| 137 | Don Cheadle, William S. Cohen, Janet Langhart Cohen | Play |
| 138 | Tim McGraw, guest co-host Joely Fisher | Play |
| 139 | Gene Wilder, Willow Bay | Play |
| 140 | John Lithgow, guest co-host Beth Ostrosky | Play |
| 141 | Patricia Arquette, Macy Gray, guest co-host Jacque Reid | Play |
| 142 | Jonathan Rhys Meyers, guest co-host Marcia Gay Harden | Play |
| 143 | Camryn Manheim, Andy Baldwin | Play |
| 144 | Jerry Stiller, guest co-host Valerie Bertinelli | Play |
| 145 | David Hyde Pierce, Martina McBride | Play |
| 146 | Lorraine Bracco, Victoria Rowell, guest co-host Jamie-Lynn Sigler | Play |
| 147 | Molly Shannon, Leeza Gibbons, guest co-host Rose McGowan | Play |
| 148 | Halle Berry, Mat Kearney | Play |
| 149 | Bill Maher | Play |
| 150 | Robert Wagner, Robert Vaughn, "The Pirate Queen" cast, guest co-host Rene Syler | Play |
| 151 | Craig Ferguson, Rue McClanahan, guest co-host Aisha Tyler | Play |
| 152 | Jessica Biel, Clyde Drexler, Olympia Dukakis, Elena Grinenko | Play |
| 153 | Sigourney Weaver, guest co-host Whoopi Goldberg | Play |
| 154 | Joan Rivers, Neil Sedaka | Play |
| 155 | Vanessa Redgrave, guest co-host Regina King | Play |
| 156 | Mia Farrow, Donny Osmond | Play |
| 157 | Tyra Banks, Heather Mills, Jonathan Roberts, guest co-host Carrie Ann Inaba | Play |
| 158 | Alec Baldwin, Edie Falco | Play |
| 159 | Masi Oka, Bill Bradley | Play |
| 160 | Judy Gold, Miranda Lambert, Natalie Portman, guest co-host Ricki Lake | Play |
| 161 | Keri Russell | Play |
| 162 | Marcia Cross, Eric Mabius, John Ratzenberger, Edyta Sliwinska, guest co-host Jenny McCarthy | Play |
| 163 | Edie Falco, Peter Krause, Natalie Portman, guest co-host Judy Gold | Play |
| 164 | James Denton, Nora Ephron, guest co-host Alison Stewart | Play |
| 165 | Hayden Panettiere, Robin Thicke, guest co-host Sarah Ferguson | Play |
| 166 | Gena Rowlands, Brooke Shields, guest co-host Goldie Hawn | Play |
| 167 | Geoffrey Rush, James Pickens Jr., Billy Ray Cyrus, guest co-host Marie Osmond | Play |
| 168 | Felicity Huffman, Dean Obeidallah | Play |
| 169 | Tyne Daly, Sharon Gless, Ali Larter, guest co-host Lee Woodruff | Play |
| 170 | David Boreanaz, William Shatner | Play |
| 171 | Dave Annable, Balthazar Getty, Kathy Griffin, Avril Lavigne, Sara Ramirez | Play |
| 172 | Cheryl Burke, Josh Holloway, Ian Ziering, guest co-host Chandra Wilson | Play |
| 173 | Teri Hatcher | Play |
| 174 | Andy Baldwin, Doug Savant | Play |
| 175 | Andy Baldwin, Tessa Horst, Dominic Monaghan, guest co-host Kassie DePaiva | Play |
| 176 | Laila Ali, Joey Fatone, Elizabeth Mitchell, Alicia Silverstone, guest co-host Sherri Shepherd | Play |
| 177 | Apolo Anton Ohno, Kathy Griffin, Korey Rowe, Dylan Avery, William Rodriguez, guest co-host Sherri Shepherd | Play |
| 178 | Jeanne Bice, The Clever Cleaver Brothers, B. Smith, David Tutera, guest co-host Padma Lakshmi | Play |
| 179 | Avril Lavigne | Play |
| 180 | Jimmy Fallon, Audra McDonald, Jeffrey Ross | Play |
| 181 | Sara Blakely, Cathleen Black, Meg Whitman, guest co-host Suze Orman | Play |
| 182 | Debra Messing, Judy Davis, Anika Noni Rose, a performance by the Broadway cast of "Legally Blonde" | Play |
| 183 | Jane Seymour, guest co-host Lori Stokes | Play |
| 184 | Wayne Brady, Ne-Yo, guest co-host Kathy Griffin | Play |
| 185 | Ross Mathews, Martha Stewart, guest co-host Kathy Griffin | Play |
| 186 | Liev Schreiber, Lynne Spears, guest co-host Sherri Shepherd | Play |
| 187 | Mario Cantone, Marg Helgenberger, guest co-host Lorraine Bracco | Play |
| 188 | Robert Iler, Burt Pugach, Linda Pugach, guest co-host Kathy Griffin | Play |
| 189 | Seth Green, Rihanna, guest co-host Kim Coles | Play |
| 190 | The Puppini Sisters, Judge Judy Sheindlin, guest co-host Rene Syler | Play |
| 191 | Anthony Michael Hall, Denis Leary, guest co-host Jacque Reid | Play |
| 192 | Blake Lewis, Michael Smerconish, Jordin Sparks, guest co-host Kim Coles | Play |
| 193 | Jessica Alba, Grace Anne Koppel, Ted Koppel, cast members from "One Life to Live", guest co-host Sherri Shepherd | Play |
| 194 | Mario Cantone, Kyra Sedgwick, guest co-host Margaret Cho | Play |
| 195 | Toby Keith, Michael Moore, guest co-host Star Parker | Play |
| 196 | Bon Jovi, guest co-host Gayle King | Play |
| 197 | Fran Drescher, Lucy Liu, guest co-hosts Gayle King, Sherri Shepherd | Play |
| 198 | Steve Carell, Steven Lamm, Wanda Sykes, guest co-host Molly Shannon | Play |
| 199 | Jackie Collins, Tina Brown, guest co-hosts Whoopi Goldberg, Sherri Shepherd | Play |
| 200 | Jaclyn Smith, John Ratzenberger, guest co-host Alexandra Wentworth | Play |
| 201 | Kelly Rowland, Jason Thompson, Billy Dee Williams, Mary Tyler Moore, guest co-host Debi Mazar | Play |
| 202 | Joan Rivers, chef Ingrid Hoffman, guest co-host Mario Cantone | Play |
| 203 | Tom Bergeron, Perez Hilton, guest co-hosts Whoopi Goldberg, Sherri Shepherd | Play |
| 204 | Harry Hamlin, Lisa Rinna, guest co-host Sherri Shepherd | Play |
| 205 | Kristin Chenoweth, guest co-host Ross Mathews | Play |
| 206 | Alan Alda, Taylor Hicks, guest co-host Sherri Shepherd | Play |
| 207 | Glenn Close, bubble performer Fan Yang, guest co-host Paula Abdul | Play |
| 208 | Ashley Judd, guest co-host Sherri Shepherd | Play |
| 209 | Amanda Bynes, guest co-host Victoria Recano | Play |
| 210 | Minnie Driver, guest co-host Maria Menounos | Play |
| 211 | Cheryl Ladd, James Marsden, guest co-host Giuliana DePandi | Play |
| 212 | Martin Sheen, Billy Ray Cyrus, guest co-host Dayna Devon | Play |
| 213 | Queen Latifah, John Travolta, guest co-host Sherri Shepherd | Play |
| 214 | Jason Priestley, Sugarland, guest co-host Nancy Grace | Play |
| 215 | George Lopez, Alan Jackson and his wife Denise, guest co-host Joan Rivers | Play |
| 216 | Jon Voight | Play |
| 217 | Julia Stiles, Zac Efron, guest co-host Chelsea Handler | Play |
| 218 | Anderson Cooper, Nina Garcia, guest co-hosts Caroline Rhea and Melissa Claire Egan | Play |
| 219 | Ashley Tisdale, Drake Bell, Josh Peck, Alyson and Amanda Michalka, children from "Are You Smarter Than a 5th Grader?", guest co-host Maria Lark | Play |
| 220 | Season 10, Episode 220 | Play |
| 221 | Season 10, Episode 220 | Play |
| 222 | Season 10, Episode 220 | Play |
| 223 | Season 10, Episode 223 | Play |
| 224 | Season 10, Episode 224 | Play |
| 225 | Season 10, Episode 225 | Play |
| 226 | Season 10, Episode 226 | Play |
| 227 | Season 10, Episode 227 | Play |
| 228 | Season 10, Episode 228 | Play |
| 229 | Season 10, Episode 229 | Play |
| 230 | Season 10, Episode 230 | Play |
| 231 | Season 10, Episode 231 | Play |
| 232 | Season 10, Episode 232 | Play |
| 233 | Season 10, Episode 233 | Play |
| 234 | Season 10, Episode 234 | Play |
| 235 | Season 10, Episode 235 | Play |
| 236 | Season 10, Episode 236 | Play |
| 237 | Season 10, Episode 237 | Play |
| 238 | Season 10, Episode 238 | Play |
| 239 | Season 10, Episode 239 | Play |
| 240 | Season 10, Episode 240 | Play |
